Shop around for prices.
There is a wide variance from store to store.  For example, we have found prices on fluoxetine (generic Prozac) to vary from $13.00 to $170.00 for 100 of 20 mg dose. 

Watch for sales on prescriptions you take regularly.  Drugstores will sometimes put commonly prescribed drugs on sale. Ask your doctor to write your prescription for a larger quantity and stock up.

Ask about generics.
While generics can save money, a word of caution is in order:  In some cases, one particular brand name drug is more effective than the generic substitute.  Be aware that the pharmacy may actually make more money on generics.  Your doctor should always have the final say.

Store drugs properly. 
Drugs need to be kept fresh in a cool, dry climate. Make sure those expensive drugs retain their effectiveness.  Certain drugs need special care and can lose potency even before the expiration date; for example, if nitroglycerin doesn't make your tongue tingle, you need a fresh bottle.

SPECIAL TIP ON PRESCRIPTIONS:
Check prices with the member warehouse stores in your area even if you’re not a member.  Most will allow non-members to buy from the pharmacy and they accept most plans.  The prices may be substantially lower! 

Prices for many of the most common drugs are now posted on the Medicare website.  Even if you aren’t eligible for the new Medicare drug cards, this is a valuable tool to help compare prices in your area.

FREE & LOW COST PRESCRIPTIONS AVAILABLE FROM DRUG COMPANIES
Many of the most commonly-prescribed drugs are available from the manufacturers for free.
The industry has now set up a one-stop web site and phone line to see if you qualify:

www.HelpingPatients.org
888-4PPA-NOW  (477-2669)